عنوان النشاط
تخليق و دراسة النمذجة الجزيئية والتقييم الأولي لخصائص مشتقات الفينوبروفين الجديدة المضادة للالتهابات والمضادة للميكروبات
Synthesis, docking study, and preliminary Anti-inflammatory and Antimicrobial Evaluation of New Fenoprofen derivatives
الجهة المنظمة
جامعة بغداد / كلية الصيدلة
تأريخ الانعقاد
2026-04-07 2026-04-07
التخصص
العلوم الطبية والصحية
مكان الانعقاد
كلية الصيدلة
نبذة مختصرة
"This study focuses on heterocyclic compounds like 1,3,4-thiadiazole and oxazole, which exhibit a broad range of therapeutic effects including antibacterial, antifungal, anti-mycobacterial, analgesic, anti-inflammatory, antipsychotic, and anticonvulsant activities. Additionally, they show potential for anticancer and HIV inhibitory actions. The aim of the study is to explore the biological potential of selected compounds through computational approaches. Molecular docking simulations were conducted using Schrödinger Maestro/Glide to predict the binding affinities and interaction profiles of the ligands with the active sites of target proteins. Pharmacokinetic and drug-likeness properties were evaluated using the QikProp module, ensuring that the compounds meet ADMET criteria. The research