عنوان النشاط
Proline derived guanidine catalysts forge extensive H-bonded architectures: a solution and solid state study
الجهة المنظمة
جامعة النهرين / كلية العلوم
تأريخ الانعقاد
2023-05-09
مكان الانعقاد
كلية العلوم
نبذة مختصرة
The preparation of a range of amino acid derived guanidine organocatalysts is reported together with their application to the Michael addition of 2-hydroxy-1,4-napthoquinone to b-nitrostyrene, achieving a maximum ee of 56%. Some insight into the mechanism was sought by using X-ray crystallography and a detailed study of the intra- and intermolecular hydrogen bonding is reported